Hyperlipoproteinemia(a) and Hyperhomocysteinemia in an Young Female with Cerebrovascular Accident

    Published on:November 2016
    Journal of Young Pharmacists, 2017; 9(1):135-136
    Case Report | doi:10.5530/jyp.2017.9.27

    Krishna Sen1, Anjan Adhikari2*, Moumita Ray2

    1Department of Medicine, Murshidabad Medical College, Berhampur, Dist. Murshidabad-742101, West Bengal, India

    2Department of Pharmacology, R. G. Kar Medical College, Kolkata-700004, West Bengal, India


    Background: Hyperhomocysteinemia is a recognized cause of cerebrovascular accident in young, in the Indian subcontinent population. But high lipoprotein(a) is not so much common and though associated with atherogenesis, no positive correlation is established till now between these. Case report: A patient presented with sudden onset of left sided hemiplegia without any recognized risk factor of atherosclerosis but a past history of miscarriage attended the Emergency in a tertiary care hospital. Her blood parameter shows Homocysteine level 19.51μmol/L and lipoprotein(a) level 580 mg/L. Computed tomography (CT) scan showed infraction in the right basal ganglion which was confirmed by Magnetic Resonance Imaging (MRI) later on. Conclusion: It is a unique type of case report as Hyperlipoproteinemia(a) is not a recognized cause of cerebrovascular accident (CVA). More study require to establish the correlation between hyperlipoproteinemia(a) & hyperhomocysteinemia and cerebrovascular accident.

    Key words: Cerebrovascular Accident, Hyperhomocystienemia, Hyperlipoprotienemia(a)

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