Pharmacognostical Studies and Evaluation of Anti-inß ammatory Activity of Ficus bengalensis Linn

    Published on:
    Journal of Young Pharmacists, 2009; 1(1):49-53
    Pharmacognosy | doi:10.4103/0975-1483.51879
    Authors:

    Patil VV, Pimprikar RB, Patil VR

    Department of Pharmaceutical Chemistry and Pharamacognosy, TVES’s College of Pharmacy, Faizpur, Maharashtra, India

    Address for correspondence: Dr. Vikas V. Patil; E-mail: vikas312@rediffmail.com

    Abstract:

    Pharmacognostical parameters for the leaves of Ficus bengalensis were studied with the aim of drawing the pharmacopoeial standards for this species: macroscopical and microscopical characters, physio-chemical constants, extractive values with different solvents, ß uorescence analysis of dry powder, its reaction after treatment with chemical reagents under visible light, and UV light at 254 nm and 366 nm. Preliminary phytochemical studies on the Ficus bengalensis leaves were conducted. The determination of these characters will aid future investigators in their pharmacological analyses of this species. The anti-inß ammatory effect of ethanolic and petroleum ether extracts of fi cus bengalensis were evaluated in experimental animals. We have determined the anti-inß ammatory activity of ethanolic and petroleum ether extracts of the bark of Ficus bengalensis by oral administration of doses of 300 and 600 mg/kg/day of body weight to healthy animals. The extracts were studied for their anti-inß ammatory activity in carrageenan-induced hind paw edema in rats and the paw volume was measured plethysmometrically at 0 3h after injection. The ethanolic and petroleum ether extracts of Ficus bengalensis, signiÞ cantly reduced (P<0.05) carrageenan-induced paw edema in rats. The ethanolic and petroleum ether extracts showed a greater anti-inß ammatory effect compared with the standard drug Indomethacin. The present results indicated the ethanolic extract of Ficus bengalensis exhibited more signiÞ cant activity than petroleum ether in the treatment of inß ammation.

     Key words: Ficus bengalensis, moraceae, vada, inß ammation, pharmacognostical, indomethacin.

     

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